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Check with your doctor before you use medicines that may cause drowsiness eg, sleep aids, muscle relaxers while you are taking Prozac; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness. The concomitant use of PROZAC with MAOIs intended to treat psychiatric disorders is contraindicated. PROZAC should also not be started in a patient who is being treated with MAOIs such as linezolid or intravenous methylene blue. These reactions have occurred with dyspnea as the only preceding symptom. These terms represent serious adverse events, but do not meet the definition for adverse drug reactions. They are included here because of their seriousness. purchase cheapest plavix payment australia

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Antidepressants increased the risk of suicidal thinking and behavior in short-term studies in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of fluoxetine or any other in a child or adolescent must balance this risk of with the clinical need. Tell your doctor right away if you become pregnant while taking this medication. Fluoxetine may cause heart defects or serious lung problems in a newborn if you take the medication during pregnancy. However, you may have a relapse of depression if you stop taking your antidepressant. Do not start or stop taking fluoxetine during pregnancy without your doctor's advice.

Changes in appetite or weight

Can different inactive ingredients -- binders and fillers -- affect the drug's quality? SSRI should be taken in the precise prescribed amount; deviating from the dose amount can result in serious side effects. In subjects with cirrhosis of the liver, the clearances of fluoxetine and its active metabolite, norfluoxetine, were decreased, thus increasing the elimination half-lives of these substances. A lower or less frequent dose of fluoxetine should be used in patients with cirrhosis. There have been reports of both increased and decreased levels when lithium was used concomitantly with fluoxetine. Cases of lithium toxicity and increased serotonergic effects have been reported.

What conditions does prozac treat

Room temperature with no light or moisture. Do not flush or wash down the drain. Suicide is a known risk of depression and certain other psychiatric disorders, and these disorders themselves are the strongest predictors of suicide. There has been a long-standing concern, however, that antidepressants may have a role in inducing worsening of depression and the emergence of suicidality in certain patients during the early phases of treatment. Pooled analyses of short-term placebo-controlled trials of antidepressant drugs SSRIs and others showed that these drugs increase the risk of suicidal thinking and behavior suicidality in children, adolescents, and young adults ages 18-24 with Major Depressive Disorder MDD and other psychiatric disorders. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction with antidepressants compared to placebo in adults aged 65 and older.



Important information

When COMT is blocked, dopamine can be retained and used more effectively, reducing Parkinson's symptoms. COMT inhibitors like and can also increase the effectiveness of levodopa. Patients should be cautioned to seek medical care immediately if they experience these symptoms. Suicide is a known risk of depression and certain other psychiatric disorders, and these disorders themselves are the strongest predictors of suicide. There has been a long-standing concern, however, that may have a role in inducing worsening of depression and the emergence of suicidality in certain patients during the early phases of treatment. Pooled analyses of short-term placebo-controlled trials of antidepressant drugs SSRIs and others showed that these drugs increase the risk of suicidal thinking and behavior suicidality in children, adolescents, and young adults ages 18-24 with Major Depressive Disorder MDD and other psychiatric disorders. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction with antidepressants compared to placebo in adults aged 65 and older. Your child's height and weight should be monitored during treatment with PROZAC. PROZAC in double-blind trials were retrospectively evaluated; no conduction abnormalities that resulted in heart block were observed. Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms. Get emergency medical help if you have signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat. However, given the long half-life and nonlinear disposition of the drug, a single-dose study is not adequate to rule out the possibility of altered pharmacokinetics in the elderly, particularly if they have systemic illness or are receiving multiple drugs for concomitant diseases. However, he adds, "it is possible that people will react differently to a different formulation. Do not stop using fluoxetine suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using fluoxetine. In some cases, a patient already receiving PROZAC therapy may require urgent treatment with linezolid or intravenous methylene blue. If acceptable alternatives to linezolid or intravenous methylene blue treatment are not available and the potential benefits of linezolid or intravenous methylene blue treatment are judged to outweigh the risks of serotonin syndrome in a particular patient, PROZAC should be stopped promptly, and linezolid or intravenous methylene blue can be administered. The patient should be monitored for symptoms of serotonin syndrome for five weeks or until 24 hours after the last dose of linezolid or intravenous methylene blue, whichever comes first. Relapse during the double-blind phase was defined as a persistent return to baseline vomiting frequency or physician judgment that the patient had relapsed. This drug is used to treat a small subset of people with narcolepsy who have excessive daytime sleepiness and cataplexy that does not respond to the other medications. It is the only drug approved by the FDA for cataplexy. It has a history of abuse as a recreational drug; therefore, the FDA has classified it as a controlled substance. MedDRA dictionary term from integrated database of placebo controlled trials of 15870 patients, of which 9673 patients received fluoxetine. Be manufactured under the same strict standards as brand-name products. Meet batch requirements for, among other things, strength, purity, and quality.



OCD have not been established

You should see some improvement in 1 to 2 weeks. It may take 4 to 5 weeks before you feel the full benefit. Prozac: An extended-release Prozac capsule should not be broken, chewed, or opened. The pill should be swallowed whole as it is designed to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time. Torsades de Pointes-type arrhythmias, and sudden death. PROZAC-treated patients were free from at endpoint than placebo-treated patients, 42% versus 28%, respectively. Do not keep outdated drugs. Dispose of unused medications as instructed on the drug label or patient information sheet. You can also check with your pharmacist about proper disposal methods. It may also be used to treat hot flashes that occur with menopause. While Prozac is expected to be a boon for Barr, Lilly's financial prospects are expected to suffer, at least in the short run. On Aug. Prozac will be sold under the trade name Sarafem for this use, says Laura Miller, a spokeswoman for Eli Lilly, which makes the drug. The following adverse reactions have been identified during post approval use of PROZAC. Because these reactions are reported voluntarily from a population of uncertain size, it is difficult to reliably estimate their frequency or evaluate a causal relationship to drug exposure. Take Prozac by mouth with or without food. Work out a plan with your doctor before reducing or stopping this medication; you should not stop taking it abruptly. You may reduce the intensity of symptoms by tapering off of this medication over time. Thus, fluoxetine may be administered with or without food. These reactions have occurred with as the only preceding symptom. tecta



What other drugs will affect prozac

Patients, their families, and their caregivers should be encouraged to be alert to the emergence of anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia psychomotor restlessness hypomania, mania, other unusual changes in behavior, worsening of depression, and suicidal ideation, especially early during antidepressant treatment and when the dose is adjusted up or down. Families and caregivers of patients should be advised to look for the emergence of such symptoms on a day-to-day basis, since changes may be abrupt. Such symptoms should be reported to the patient's prescriber or health professional, especially if they are severe, abrupt in onset, or were not part of the patient's presenting symptoms. Avoid using alcohol with this medication as it may worsen potential side effects. Take this medication by mouth as directed by your doctor, usually once daily in the morning. If you are taking this medication twice a day, your doctor may direct you to take it in the morning and at noon. Jermain DM, Hughes PL, Follender AB. Potential fluoxetine-selegiline interaction. USFood and Drug Administration. FDA Drug Safety Communication: Updated information about the drug interaction between linezolid Zyvox and serotonergic psychiatric medications. Boyer EW, Shannon M. The serotonin syndrome. Some people may be at risk for eye problems from Prozac. Your doctor may want you to have an eye exam to see if you are at risk for these eye problems. Call your doctor right away if you have eye pain, vision changes, or swelling or redness in or around the eye. You place the box on a table or desk where you can do paperwork, read, or make phone calls. You do not need to look directly into the light. Patients should also be advised of the signs and symptoms associated with a severe allergic reaction, including swelling of the face, eyes, or mouth, or have trouble breathing. Patients should be cautioned to seek medical care immediately if they experience these symptoms. Seek emergency medical attention if you think you have taken too much of this Prozac or Zoloft. Many drugs can interact with fluoxetine. Not all possible interactions are listed here. Antidepressant efficacy was demonstrated with olanzapine and fluoxetine in combination with a dose range of olanzapine 6 to 12 mg and fluoxetine 25 to 50 mg. Safety of co-administration of doses above 18 mg olanzapine with 75 mg fluoxetine has not been evaluated in clinical studies. Periodically re-examine the need for continued pharmacotherapy. Studies at clinically relevant doses in man have demonstrated that fluoxetine blocks the uptake of serotonin into human platelets. Studies in animals also suggest that fluoxetine is a much more potent uptake inhibitor of serotonin than of norepinephrine. No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out. Since the introduction of PROZAC, systemic reactions, possibly related to vasculitis and including -like syndrome, have developed in patients with rash. Although these reactions are rare, they may be serious, involving the lung, kidney, or liver. Death has been reported to occur in association with these systemic reactions. Do not take fluoxetine together with Orap Mellaril or a monoamine oxidase inhibitor MAOI such as furazolidone Furoxone Marplan Nardil Azilect Eldepryl, Emsam, Zelapar or Parnate. A dangerous drug interaction could occur, leading to serious side effects. marex.info venlafaxine



How should I store SARAFEM?

Fluoxetine and norfluoxetine have been shown to have no genotoxic effects based on the following assays: bacterial mutation assay, assay in cultured rat hepatocytes, mouse assay, and in vivo sister chromatid exchange assay in Chinese hamster cells. Fluoxetine can stay in your body for many weeks after your last dose and may interact with many other medications. Before using any medication, tell your doctor or pharmacist if you have taken fluoxetine in the previous 5 weeks. Must be the same in strength and dosage whether pill or capsule as brand-name drugs. Paxil paroxetine hydrochloride US prescribing information. Apotex Technologies July, 2014. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using fluoxetine, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems heart failure, slow heartbeat, QT prolongation in the EKG family history of certain heart problems QT prolongation in the EKG, sudden cardiac death. Do not stop using fluoxetine suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using fluoxetine. When using PROZAC and olanzapine in combination, also refer to the Medication Guide for Symbyax. generic condyline buy uk



How should i take prozac

What sort of rigorous testing is West talking about? Patients should be advised to notify their physician if they intend to breast-feed an infant during therapy. AUC in pediatric patients at the MRHD and learning deficit at the high dose and reproductive functional impairment decreased mating at all doses and impaired fertility at the high dose. In addition, the testicular and epididymal lesions and decreased concentrations found in high dose group were also observed, indicating that the drug effects on reproductive organs are irreversible. The reversibility of fluoxetine-induced muscle damage was not assessed. Fluoxetine is extensively metabolized in the liver to norfluoxetine and a number of other unidentified metabolites. The only identified active metabolite, norfluoxetine, is formed by demethylation of fluoxetine. In animal models, S-norfluoxetine is a potent and selective inhibitor of serotonin uptake and has activity essentially equivalent to R- or S-fluoxetine. R-norfluoxetine is significantly less potent than the parent drug in the inhibition of serotonin uptake. The primary route of elimination appears to be hepatic metabolism to inactive metabolites excreted by the kidney. This drug is available at a higher level co-pay. Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies. WebMD. "No two people are exactly the same. An inert ingredient -- a binder -- is different in this formulation than in another formulation. Periodically reassess to determine the need for treatment. Zoloft the generic brand though for a week now and am very pleased. It has lifted my spirits, helps me sleep at night, and curbs my appetite. I have no bad side effects. Very satisifed! Drink six to 10 glasses of water a day. These are not all the possible side effects of SARAFEM. Stanford SC, Stanford BJ, Gillman PK. Risk of severe serotonin toxicity following co-administration of methylene blue and serotonin reuptake inhibitors: an update on a case report of post-operative delirium. This drug is available at a middle level co-pay. It is in a class of called selective reuptake inhibitors SSRIs a class that includes and . Fluoxetine affects neurotransmitters, the chemicals that nerves within the brain use to communicate with each other. Neurotransmitters are manufactured and released by nerves and then travel and attach to nearby nerves. Thus, neurotransmitters can be thought of as the communication system of the brain. Serotonin is one neurotransmitter that is released by nerves in the brain. The serotonin either travels across the space between nerves and attaches to receptors on the surface of nearby nerves or it attaches to receptors on the surface of the nerve that produced it, to be taken up by the nerve and released again a process referred to as re-uptake. generic vs brand name serevent



What is prozac

No reports involved the administration of methylene blue by other routes such as oral tablets or local tissue injection or at lower doses. There may be circumstances when it is necessary to initiate treatment with an such as linezolid or intravenous methylene blue in a patient taking PROZAC. Treatment-emergent adverse reactions in clinical trials with PROZAC Weekly were similar to the adverse reactions reported by patients in clinical trials with PROZAC daily. In a placebo-controlled clinical trial, more patients taking PROZAC Weekly reported diarrhea than patients taking placebo 10% versus 3%, respectively or taking PROZAC 20 mg daily 10% versus 5%, respectively. Steady-state levels after prolonged dosing are similar to levels seen at 4 to 5 weeks. Tofranil is an older medication, known as a tricyclic antidepressant, which works by making more of the neurotransmitters serotonin and norepinephrine available. If you are taking any prescription drugs or regularly taking supplements, ask your doctor about any possible interactions before taking Prozac. Patients should be advised to consult with their healthcare provider if their symptoms do not improve with PROZAC.



Prozac forms and strengths

PROZAC should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. If you believe you may be overdosing on Prozac, contact a poison help line, call your healthcare provider, and seek urgent medical care right away. Prozac overdose is a medical emergency and should be treated as quickly as possible. These features are consistent with either a direct toxic effect of SSRIs and SNRIs or, possibly, a drug discontinuation syndrome. Pristiq desvenlafaxine succinate US prescribing information. Wyeth Pharmaceuticals, Inc. December, 2013. How should I take fluoxetine Prozac? How should I store PROZAC? Make all providers aware of all the drugs you are taking. It may harm them. If you plan to have surgery, let your surgeon know that you are taking this medication. Fournier tells WebMD. "We were interested in whether there was a clinically meaningful difference. PROZAC. Seethe end of this Medication Guide for a complete list of ingredients in PROZAC. SARAFEM, and other CNS acting drugs is required. Peter C, Hongwan D, Kupfer A, Lauterburg BH. Pharmacokinetics and organ distribution of intravenous and oral methylene blue. It is not known if PROZAC will harmyour unborn baby. Talk to your healthcare provider about the benefits and risksof treating depression during pregnancy. Your pharmacist can provide more information about fluoxetine. purchase pyridostigmine venezuela



Before taking prozac

Zoloft for two days and cannot stop crying and have suicidal urges. I think I should quit and get back on prozac. Call your doctor for medical advice about side effects. What should I discuss with my healthcare provider before taking fluoxetine Prozac? Most patients with can initially be treated with drugs that adequately alleviate their symptoms. If or when are not sufficiently effective, new, highly effective and safe surgical treatments are also available. Patients should be advised that hyponatremia has been reported as a result of treatment with SNRIs and SSRIs, including PROZAC. Signs and symptoms of hyponatremia include headache, difficulty concentrating, memory impairment, confusion, weakness, and unsteadiness, which may lead to falls. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Tell your healthcare provider about all the medicines that you take, includingprescription and non-prescription medicines, vitamins, and herbal supplements. PROZAC should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. All pregnancies have a background risk of birth defects, loss, or other adverse outcome regardless of drug exposure. Always keep medications out of the reach of children. Zoloft sertraline US prescribing information. Pfizer Inc. December, 2012. Safety of co-administration of doses above 18 mg olanzapine with 75 mg fluoxetine has not been evaluated in clinical studies. The age of the and the mother's medical history should factor into any decisions about prescribing Prozac, according to Anderson. cheapest cordarone online money order



Prozac dosing information

Check to be sure a light box filters out harmful ultraviolet light. You should not use fluoxetine if you also take pimozide or thioridazine, or if you are being treated with methylene blue injection. Zoloft and Prozac can both cause side effects that may impair your thinking or reactions. Actions that require focus and alertness driving, operating machinery should be avoided while on SSRI medication. For specific information about overdosage with olanzapine and fluoxetine in combination, refer to the Overdosage section of the package insert. PROZAC monotherapy is not indicated for the treatment of depressive episodes associated with Bipolar I Disorder. As with other SSRIs, decreased has been observed in association with the use of fluoxetine in children and adolescent patients. Zonneveld AM, Hagenaars M, Voermans NC, Gelissen HP, Claassen JA. Life-threatening serotonin syndrome following a single dose of a serotonin reuptake inhibitor during maintenance therapy with a monoamine oxidase inhibitor. SNRIs and SSRIs, including fluoxetine, may increase the risk of bleeding reactions. Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs, warfarin, and other anti-coagulants may add to this risk. Case reports and epidemiological studies case-control and cohort design have demonstrated an association between use of drugs that interfere with serotonin and the occurrence of gastrointestinal bleeding. In neither patient was there an unequivocal diagnosis, but one was considered to have a leukocytoclastic vasculitis, and the other, a severe desquamating syndrome that was considered variously to be a vasculitis or erythema multiforme. Other patients have had systemic syndromes suggestive of serum sickness. When treating a pregnant woman with PROZAC, the physician should carefully consider both the potential risks of taking an SSRI, along with the established benefits of treating depression with an antidepressant. Although changes in sexual desire, sexual performance, and sexual satisfaction often occur as manifestations of a psychiatric disorder, they may also be a consequence of pharmacologic treatment. In particular, some evidence suggests that SSRIs can cause such untoward sexual experiences. Reliable estimates of the incidence and severity of untoward experiences involving sexual desire, performance, and satisfaction are difficult to obtain, however, in part because patients and physicians may be reluctant to discuss them. Accordingly, estimates of the incidence of untoward sexual experience and performance, cited in product labeling, are likely to underestimate their actual incidence. Patients in these 3 studies had moderate to severe bulimia with median binge-eating and vomiting frequencies ranging from 7 to 10 per week and 5 to 9 per week, respectively. In these 3 studies, PROZAC 60 mg, but not 20 mg, was statistically significantly superior to placebo in reducing the number of binge-eating and vomiting episodes per week. The statistically significantly superior effect of 60 mg versus placebo was present as early as Week 1 and persisted throughout each study. The PROZAC-related reduction in bulimic episodes appeared to be independent of baseline depression as assessed by the Hamilton Depression Rating Scale. In each of these 3 studies, the treatment effect, as measured by differences between PROZAC 60 mg and placebo on median reduction from baseline in frequency of bulimic behaviors at endpoint, ranged from 1 to 2 episodes per week for binge-eating and 2 to 4 episodes per week for vomiting. The size of the effect was related to baseline frequency, with greater reductions seen in patients with higher baseline frequencies. Although some patients achieved freedom from binge-eating and purging as a result of treatment, for the majority, the benefit was a partial reduction in the frequency of binge-eating and purging. Symptoms of a fluoxetine Prozac overdose may include nausea, vomiting, fever, sleepiness, rapid or uneven heartbeat, confusion, fainting, seizures, or coma. Use Prozac with caution in the ELDERLY; they may be more sensitive to its effects, especially low blood sodium levels. Dec. 3, 1999 Atlanta -- Many women continue to use the while they breastfeed, despite the concerns expressed by the American Academy of Pediatrics, the FDA, and the manufacturer of the drug. One likely reason: There's been little research to back up those concerns, until now. reductil



List of prozac side effects

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment. The infants of the mothers who continued to take Prozac were significantly lower in weight than infants who were breastfed by mothers not on the drug. Between two weeks and six months of age the average deficit in weight was just under 14 ounces. SSRIs help maintain the level of serotonin, a chemical in the brain that is important in mood control. Cymbalta duloxetine hydrochloride US prescribing information. Eli Lilly and Company June, 2015. AUC for thioridazine in the slow hydroxylators compared with the rapid hydroxylators. The rate of debrisoquin hydroxylation is felt to depend on the level of CYP2D6 isozyme activity. Thus, this study suggests that drugs which inhibit CYP2D6, such as certain SSRIs, including fluoxetine, will produce elevated plasma levels of thioridazine. Do not suddenly stop taking Prozac without checking with your doctor. Side effects may occur. They may include mental or mood changes, numbness or tingling of the skin, dizziness, confusion, headache, trouble sleeping, or unusual tiredness. You will be closely monitored when you start Prozac and whenever a change in dose is made. Tell your doctor if your condition does not improve or if it worsens. It's been prescribed to some 38 million patients worldwide since 1986, making it the world's most popular antidepressant. Included as part of the PRECAUTIONS section. Suchowersky O, deVries JD. Interaction of fluoxetine and selegiline. High serotonin levels may cause changes in body temperature, blood pressure and behavior, leading to a medical condition called Serotonin Syndrome. Serotonin Syndrome may be life threatening. lamisil



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Prozac side effects

Consider additional dose increases after several more weeks if insufficient clinical improvement is observed. Take PROZAC exactly as prescribed. Your healthcare provider may need to change the dose of PROZAC until it is the right dose for you. The development of a potentially life-threatening serotonin syndrome has been reported with SNRIs and SSRIs, including PROZAC, alone but particularly with concomitant use of other serotonergic drugs including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, amphetamines, and St. John's Wort and with drugs that impair metabolism of serotonin in particular, MAOIs, both those intended to treat psychiatric disorders and also others, such as linezolid and intravenous methylene blue.

How to take prozac

In premarketing clinical trials, 2 patients are known to have developed a serious systemic illness. SNRIs and SSRIs, including PROZAC. In many cases, this hyponatremia appears to be the result of the syndrome of inappropriate secretion SIADH. Fluoxetine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby. This list is not complete and many other drugs can interact with fluoxetine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Use of prozac

How should I store this medication? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. It may take up to 4 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve. Patients should be advised to call their doctor if they experience any increased or unusual bruising or bleeding while taking PROZAC.

Read all labels carefully

The effect of PROZAC on in humans is unknown. However, because fluoxetine crosses the placenta and because of the possibility that fluoxetine may have adverse effects on the newborn, fluoxetine should be used during labor and delivery only if the potential benefit justifies the potential risk to the fetus. Do not start PROZAC if you stopped taking an MAOI in the last 2 weeksunless directed to do so by your physician. Keep a drug calendar and note every time you take a dose. Because of the long elimination half-lives of the parent drug and its major active metabolite, changes in dose will not be fully reflected in plasma for several weeks, affecting both strategies for titration to final dose and withdrawal from treatment.

There are no clinical studies establishing the benefit of the combined use of ECT and fluoxetine. There have been rare reports of prolonged seizures in patients on fluoxetine receiving ECT treatment. What is the most important information I should know about fluoxetine Prozac? What are the possible side effects of fluoxetine Prozac, Prozac Weekly, Rapiflux, Sarafem, Selfemra? Some patients may experience withdrawal reactions upon stopping fluoxetine. brand cozaar generic

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